Police have cordoned off a house in Paddington.(ABC News: Elise Worthington)
Police looking for two men from Sydney's eastern suburbs say they have found blood in two different locations.
Possessions of 29-year-old Luke Davies were found in a skip-bin on Wilbar Avenue in Cronulla about 11am on Wednesday.
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Police have called on Luke or Jesse, or any of their friends with information to come forward.
They would not be drawn on the possibility of a murder-suicide, but they are not ruling out anything at this stage.
Police have only been able to contact the Jesse Baird's next-of-kin 15 minutes ago, due to legal issues.
Detectives have not ruled out any suspects at this point.
All the forensic testing is currently being done, and police are unsure whether it is related to either of the men, Detective Superintendent Jodi Radmore said.
Witnesses have told police they heard shouting early on Monday morning in Paddington.
Police are still investigating this line of inquiry.
"Witnesses described a verbal argument, but it wasn't reported to police at the time, it was only reported yesterday. "
Detective Superintendent Jodi Radmore.
A significant post went up online on Tuesday evening, Detective Superintendent Jodi Radmore confirmed.
"The only conclusion that can be drawn from that, someone was using social media on Tuesday evening."
"Any of the friends of Luke or Jesse, if any of the friends know of their whereabouts please contact police", Detective Superintendent Jodi Radmore said.
"All lines of inquiry are currently open to investigators".
Detective Superintendent Jodi Radmore said blood was found in the Cronulla skip-bin and the Paddington home.
She said they have grave concerns for at least one of the men.
Detective Superintendent Jodi Radmore has confirmed police are investigating the disappearance of two men.
Police have confirmed both men were in a relationship.
They have asked either of the missing men to come forward.
Luke Davies was last located in Paddington on Monday.
He has not been seen since.
Detective Superintendent Jodi Radmore will be giving an update on his disappearance soon.
Officers then attended a home on Brown Street in Paddington about 1pm yesterday, and "immediately established a crime scene", NSW Police said in a statement.
Police are searching for Luke Davies, left, and Jesse Baird, right.(Instagram)
Detectives then went to Mr Davies's home in Waterloo, but they have not been able to locate him.
Police are also searching for his partner, 26-year-old Jesse Baird, who they say can assist with their inquiries.
Mr Baird worked for Network 10 for more than seven years, including reporting stints for Studio 10, and presenting Totally Wild, according to his LinkedIn profile.
NSW Police believe 26-year-old Jesse Baird can help with their investigations. (Supplied)
Detective Superintendent Jodi Radmore this afternoon confirmed police were investigating the disappearance of two men.
They have asked either of the missing men to come forward.
Superintendent Radmore said blood was found in the skip-bin and the Paddington home and that police had grave concerns for at least one of the men.
"Any of the friends of Luke or Jesse, if any of the friends know of their whereabouts please contact police", Superintendent Jodi Radmore said.
Luke Davies has been missing since Monday.(Supplied: NSW Police)
"All lines of inquiry are currently open to investigators."
Witnesses have told police they heard shouting early on Monday morning in Paddington and are still investigating this line of inquiry.
NSW Police believe Mr Davies visited Paddington on Monday, and has not been seen since. He has not attended work, nor can his family contact him.
Police are appealing for any information that might lead to Mr Davies's location.
Police officers enter a house in Paddington.(ABC News: Alexander Lewis)